Signs of Parkinson's disease
Parkinsonism is manifested by slowing movements and reduced amplitude (bradykinesia), stiffness, typical increase in muscle tone (stiffness) and trembling of the limbs at rest, so says Dr. Denis Slinkin.
Parkinsonism syndrome may occur in different states:
neurodegenerative: Parkinson's disease, multisystem atrophy, progressive supernuclear paralysis, etc.
inherited nervous system diseases: Huntington's disease, Wilson's disease, etc.
secondary brain damage: infectious, toxic, induced medication, vascular parkinsonism and a number of others.
Classic Parkinson's Disease accounts for over 70% of parkinsonism cases. Parkinson's disease is a common disease, occurring at a frequency of 150-200 per 100,000 inhabitants.
Most Parkinson's disease affects people over the age of 60. It is also believed that later age is associated with a higher risk of the disease, although there are earlier forms of the disease. There are several forms of Parkinson's disease for which some heredity and intergenerational transmission can be traced.
However, in most cases, inheritance is not traceable, but only transmitted through a higher risk of disease, a predisposition to it, says Dr. Denis Slinkin.
What happens in the body in case of disease?
Dr. Denis Slinkin states that Parkinson's disease is a typical example of neurodegenerative disease in which neurons of a certain part of the brain, a black substance, die.
This leads to a deficit of the most important substance - dopamine, which in turn causes the clinical manifestations of the disease - bradykinesia, stiffness and tremor of rest, instability and slouch, as well as a wide range of symptoms not related to movement (low smell, depression, sleep disturbance, low blood pressure, constipation, increased urination, increased salivation and sweating).